TWiV 1361: Ancient Viral Sword and Shield

About this episode

TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a host defense response to microbial infection in the brain. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode • Support science education at MicrobeTV • Bob Tesh dies (Galv News) • Comment on propsed changes to NIH peer review (NIH) • NIH peer review proposed changes (Forbes) • Ancient RNA guided DNA recognition (Science) • Noncontiguous geometric triplex (Science) • p-tau has anti-herpes virus activity (Nat Neurosci) • Letters read on TWiV 1361 • Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – APoD September 14: Origins of Elements Alan – Redshirts, by John Scalzi Vincent – Prone to Bruise by David Molesky he’s at Spring/Break till 9/28 Listener Pick Anne – Nikon Small World in Motion Competition Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in thi