Are GLP-1s the First Longevity Drugs? | Lifespan with Dr. David Sinclair - S2, Ep. 11

About this episode

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives while supporting medical research into breakthroughs to improve all lives. We’re building the world’s largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks. __________________________________________ Ozempic and GLP-1s transformed weight loss. Could they also extend lifespan? In this episode, David and Matt look at the emerging science behind that question. They examine a recent study in which semaglutide extended lifespan in female mice, evidence that GLP-1s may influence multiple hallmarks of aging, and early human research examining biological aging. They also dig into how these drugs work, the potential role of the brain, the promise and unanswered questions around microdosing, and what the next generation of GLP-1 therapies could mean for longevity medicine. As David puts it, this class of drugs “might be the world’s first effective longevity medicines.” __________________________________________ Partners of the Lif