ParasocialDownload on theApp Store

The Human Upgrade: Biohacking for Longevity & Performance

Brain-Cleaning Beds, Forever Chemicals, Peptide Freedom, Coffee for Your Heart, and More : 1568

10 min

3 min preview

Listen to the full episode

Do not have it yet? Parasocial is a podcast player by Super Simple.

About this episode

Scientists Test Vibrating Mattress To Help Clear Alzheimer's-Related Proteins From The Brain Researchers at the University of Oulu in Finland tested a vibrating mattress combined with nitroglycerin, a blood-vessel-relaxing drug, in 29 healthy adults and found that blood levels of amyloid-beta 42 increased approximately 35% following the combined treatment. Published in Nature Communications, the study also identified MRI changes suggesting altered cerebrospinal fluid dynamics, potentially involving the glymphatic system and mechanosensitive Piezo1 ion channels. While the results suggest increased movement of brain-associated proteins into circulation, they do not establish that Alzheimer's plaques were removed or that cognition improved. Host Dave Asprey explores the potential of mechanical stimulation, nitric oxide signaling, and brain waste clearance as emerging approaches to neurodegenerative disease prevention, and why sleep and vascular health remain essential to protecting long-term cognitive performance. Sources: https://doi.org/10.1038/s41467-026-78894-y ~~~ Yale Researchers Discover Taurine Controls A Key Inflammatory Switch Linked To Aging Yale researchers i

Brain-Cleaning Beds, Forever Chemicals, Peptide Freedom, Coffee for Your Heart, and More : 1568 — The Human Upgrade: Biohacking for Longevity & Performance